| - | MAIN |
| R64 | Katherine Johnston (WASHUW) def. Taylor Goldman (RHIT) 6-1, 6-1 |
| R32 | Katherine Johnston (WASHUW) def. Sophia Strupovets (LFC) 7-6 (7-4), 6-0 |
| R16 | Sylwia Mikos (CHI) def. Katherine Johnston (WASHUW) 6-2, 6-1 |
| R64 | Lily McCloskey (CWRU) def. Amber Edmonds (WASHUW) 6-2, 6-4 |
| C-R32-Q | Amber Edmonds (WASHUW) def. Cristina Borunda (MILLIKIN) 6-0, 6-0 |
| C-QF | Amber Edmonds (WASHUW) def. Taylor Goldman (RHIT) 6-3, 6-1 |
| C-SF | Amber Edmonds (WASHUW) def. Madeline Kavenagh (JCU) 6-2, 6-0 |
| C-F | Amber Edmonds (WASHUW) def. Shadia Amado Aguad (KEN) 6-4, 4-6, 11-9 |
| R64 | Karen Gao (WASHUW) def. Maddie Hurley (KAL) 6-1, 6-3 |
| R32 | Karen Gao (WASHUW) def. Anna-Maria Huebel (AUGIE) 6-4, 6-3 |
| R16 | Radha Patel (CWRU) def. Karen Gao (WASHUW) 6-7 (9-11), 6-3, 6-3 |
| R64 | Eleanor Archer (WASHUW) def. Ella Frantz (AND) 6-0, 6-0 |
| R32 | Eleanor Archer (WASHUW) def. Lydia Zafeiri (OBE) 6-4, 6-1 |
| R16 | Oliwia Mikos (CHI) def. Eleanor Archer (WASHUW) 6-2, 6-2 |
| R64 | Nina Moravek (WASHUW) def. Saray Hernandez Cisn (PRIN) 6-0, 6-0 |
| R32 | Nina Moravek (WASHUW) def. Lanie Carder (GREEN) 6-0, 6-0 |
| R16 | Eleni Lazaridou (KEN) def. Nina Moravek (WASHUW) 6-2, 3-6, 6-4 |
| - | BLUE |
| QF | Randi Hendricks (WASHUW) def. Amelia Bronfman (OBE) 6-3, 6-0 |
| SF | Chloe Ku (CWRU) def. Randi Hendricks (WASHUW) 6-3, 3-6, 10-4 |
| - | GREEN |
| R16 | Katie Finerman (WASHUW) def. Evelyn Deren (JCU) 8-1 |
| QF | Katie Finerman (WASHUW) def. Sophia Pischalko (WIT) 6-1, 6-2 |
| SF | Elsa Syed (CWRU) def. Katie Finerman (WASHUW) 6-1, 6-3 |
| - | RED |
| QF | Carolyn Tsung (WASHUW) def. Madisen Cherry (EC) 7-5, 6-0 |
| SF | Rena Lin (CHI) def. Carolyn Tsung (WASHUW) 6-3, 6-3 |
| - | YELLOW |
| QF | Emily Chiasson (WASHUW) def. Caroline Kittle (DEN) 6-1, 6-1 |
| SF | Emily Chiasson (WASHUW) def. Lauren Khou (CHI) 2-6, 7-5, 10-2 |
| F | Brooke Pedersen (CHI) def. Emily Chiasson (WASHUW) 7-6 (7-2), 1-6, 10-7 |
